Nucleosome ctDNA (human, BDXXP4)

Nucleosomal ctDNA (n-ctDNA): Reference material with the lowest mutation background noise in the industry.

  • Reference material with above-average low error rate, enables lowest LOB/LOD/LOQ* for NGS assays including MRD** tests
  • Very good library conversion rate

This cfDNA is intensively characterized human cfDNA from a SensID proprietary lymphoblastoid cell line (BDXXP4). Production from other cell lines possible on request.

Due to the patient-like fragmentation pattern very well suited for liquid biopsy investigations in your laboratory or R&D department as well as clinical studies.

SKU: SID-000128 Category:

Product description

Also available as a customized product tailored to your needs!

OEM options:

If you need materials as in kit controls or as a third-party control for validation of your kits at customer labs, please contact us via:

How to create your full workflow plasma control material based on SID-000128:

We recommend the use of our human DNA-free plasma products to produce complete workflow controls with this product. Blend the cfDNA as necessary with the DNA depleted plasma to receive plasma materials with the necessary DNA concentrations.

Choose your plasma volume options :

This product is ideally suited for digital PCR and/or Next Generation Sequencing (NGS). Especially for
– validation and development of sequencing protocols (e.g. Amplicon sequencing) and PCR protocols
– to determine the detection limit of the method

Buffer: Tris-EDTA (10 mM Tris, 1 mM EDTA), pH 8.0

Storage: 2-8 °C

Shelf life:
Stable up to 24 months after date of manufacture (as supplied)

Quality assurance

Fragment size determination: Tapestation

Allele frequency/copy number (if indicated): dPCR

Quantification (metrologically traceable):

  • dsDNA measurement (fluorometric)

Technical background

Origin: SensID’s own proprietary cell line BDXXP4
Also available on request: The Genome In A Bottle (GIAB) cell line from the Personal Genome Project (PGB): GM24385 (HG002- NA24385 – huAA53E0)

– cell line specific sequencing files: on request

The results show BDXXP4 is a well suited wild type cell line, determined by WES (Whole Exome Sequencing).

* Limit of Blank/Limit of Detection/Limit of Quantification,

** Minimal Residual Disease


Certificate of Analysis (COA):

other documents:

Instructions For Use (IFU)

Safety Data Sheet (SDS)

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